Abstract #3900

Evaluating Multiband Single Echo and Multi-Echo Sequences With and Without Arterial Spin Labeling for Cerebrovascular Reactivity Calculations

Alexander D. Cohen¹, Baolian Yang², Brice Fernandez³, Suchandrima Banerjee⁴, and Yang Wang¹

¹Medical College of Wisconsin, Milwaukee, WI, United States, ²GE Healthcare, Waukesha, WI, United States, ³GE Healthcare, Buc, France, ⁴GE Healthcare, Menlo Park, CA, United States

A multiband (MB) multi-echo (ME) pseudocontinuous arterial spin labeling (pCASL) sequence has shown improved cerebrovascular reactivity (CVR) calculations compared to a single echo; however, pCASL significantly increases TR. This study compared a MBME pCASL sequence to MBME and MB single echo acquisitions for the calculation of CVR. TSNR was higher for the MBME pCASL sequence compared to the MBME and MBMS sequences, and mean CVR was comparable between all sequences. The ME sequences had improved quality in areas with high susceptibility. Despite significantly longer TR, the MBME pCASL sequence performed comparably to the MBME sequence, while simultaneously providing ASL data.

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