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Abstract #3899

Comparing Multiband Single Echo and Multi-echo Sequences With and Without Arterial Spin Labeling for Task Activation

Alexander D. Cohen1, Baolian Yang2, Brice Fernandez3, Suchandrima Banerjee4, and Yang Wang1
1Medical College of Wisconsin, Milwaukee, WI, United States, 2GE Healthcare, Waukesha, WI, United States, 3GE Healthcare, Buc, France, 4GE Healthcare, Menlo Park, CA, United States

Multi-echo functional MRI has shown increased BOLD sensitivity compared to single echo acquisitions; however, it suffers from increased TR, especially when combined with arterial spin labeling (ASL). This study compared multiband multi-echo scans with and without pseudocontinuous ASL to a multiband single echo acquisition during a visual task. Temporal signal to noise and group task activation was higher for the multi-echo scans. Furthermore, the multi-echo PCASL sequence showed similar activation to multi-echo alone despite significantly higher TR. This study showed the benefits of ME acquisitions for task fMRI, despite higher TR. The addition of ASL did not reduce task activation.

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