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Abstract #3917

Assessing drug cue-induced brain response in heroin dependents treated by methadone maintenance and protracted abstinence measures one year

Xuan Wei1
1radiology department, Tangdu Hospital, the Fourth Military Medical University, Xi'an, China

Our research aims to compare PA with MMT to reveal which abstinence way is better to recover the brain function in heroin-dependent individuals. Twenty-four heroin-dependent male males with about 12 months of PA, 21 heroin-dependent male patients stabilized on MMT for about 12 months and 20 demographically HC completed an event-related fMRI task including heroin-related and neutral cues. In the last part of this study, we proved PA is closer to HC group. This study showed PA is more beneficial for the heroin-dependent patients to lower the salience value of drug related cues, in turn to reduce relapse risks.

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