Our research aims to compare PA with MMT to reveal which abstinence way is better to recover the brain function in heroin-dependent individuals. Twenty-four heroin-dependent male males with about 12 months of PA, 21 heroin-dependent male patients stabilized on MMT for about 12 months and 20 demographically HC completed an event-related fMRI task including heroin-related and neutral cues. In the last part of this study, we proved PA is closer to HC group. This study showed PA is more beneficial for the heroin-dependent patients to lower the salience value of drug related cues, in turn to reduce relapse risks.
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