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Abstract #3974

Resting-state Functional Connectivity during Voluntary Mouth Breathing

Chan-A Park1, Ju-Yeon Jung2, Yeong-Bae Lee3,4, and Chang-Ki Kang2,4,5
1Biomedical Engineering Research Center, Gachon University, Incheon, Korea, Republic of, 2Department of Healthy Science, Gachon University Graduate School, Incheon, Korea, Republic of, 3Department of Neurology, Gachon University Gil Medical Center, Incheon, Korea, Republic of, 4Neuroscience Research Institute, Gachon University, Incheon, Korea, Republic of, 5Department of Radiological Science, Gachon University, Incheon, Korea, Republic of

The purpose of the study is to examine the difference of the functional connectivity between the nasal and mouth breathing conditions in healthy subjects using resting-state functional magnetic resonance imaging via seed-based correlation analysis. “Mouth>Nose” contrast had 5 seeds and 23 connecting pairs, however, 6 seeds and 14 pairs in the “Mouth<Nose” contrast. Especially, caudate had the most number of connections of salience networks, supramarginal gyrus, insular cortex, central opercular cortex, supramarginal gyrus, and parietal operculum in “Mouth>Nose” contrast. These indicated that the limbic system regulates the resting-state functional connectivity during the voluntary mouth breathing compared the nasal breathing.

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