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Abstract #3999

Resting-state Functional MRI Investigation of Whiplash Associated Disorder

James Higgins1, James Elliott2, and Todd Parrish1
1Northwestern University, Chicago, IL, United States, 2The University of Syndney, Sydney, Australia

Many individuals who suffer an initial whiplash injury develop a chronic condition known as whiplash associated disorder (WAD). In this study, 23 participants with WAD underwent resting-state fMRI along with a fat-water scan of the cervical region to assess muscle fat infiltration (MFI), which has been demonstrated as a marker of disorder severity. Brain network modularity was calculated from the RS-fMRI data and associations between modularity and clinical measures were investigated. An association was discovered between modularity and MFI which appeared to be independent of demographic variables as well as scan motion.

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