Most of current multinuclear MR experiments are performed by doing mono-nuclear acquisitions separately, followed by registering images obtained from each one. To reduce the total measurement time and experiment registration error, a novel four-frequency 1H/19F/23Na/31P RF coil system was developed and evaluated. Our performance evaluations showed that all coil arrays were sufficiently matched, decoupled and detuned when working simultaneously, and the unbalance of amplitude and phase increments generated by the interface circuits were well controlled, thus can be expected to generate a uniform B1+ field and high SNR images for simultaneous 1H/19F/23Na MRI and for 31P MRS.
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