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Abstract #4127

3D PRF Thermometry of the Liver

Waqas Majeed1, Sunil Patil1, Pan Su1, Rainer Schneider2, Henrik Odéen3, Dennis L. Parker3, John Roberts3, Jiachen Zhuo4, and Himanshu Bhat1
1Siemens Medical Solutions USA Inc., Malvern, PA, United States, 2Siemens Healthcare GmbH, Erlangen, Germany, 3Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, 4Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, United States

Anatomical misregistration and background phase variation due to physiological motion are two major sources of inaccuracy in PRF thermometry of the liver. We propose a pipeline consisting of 3D segmented EPI acquisition, 3D deformable motion correction and PCA-based background phase correction for liver thermometry. 3D acquisition results in an increase in SNR and makes 3D registration possible. PCA-based background phase correction improves ΔT quality over a more commonly used dictionary-based method. The proposed pipeline was used to achieve 75th percentile ΔT bias and standard deviation values of 1.70°C and 1.65°C respectively over whole-liver in one healthy volunteer.

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