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Abstract #4128

Development of T1-based Skull Thermometry using a 3D Spiral Ultra-Short Echo Time Sequence

Yekaterina K Gilbo1, Helen Sporkin2, Samuel W Fielden3, John P Mugler4, Grady W Miller4, Steven P Allen2, and Craig H Meyer2
1University of Virginia, Charlottesville, VA, United States, 2Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 3Department of Imaging Sciences & Innovation, Geisenger, Danville, PA, United States, 4Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States

Skull temperature monitoring is important for MR-guided focused ultrasound (MRgFUS), as the skull is highly absorptive to acoustic energy. T1 thermometry uses T1 mapping to observe a linear increase in T1 with temperature but requires long acquisitions. Here we compare T1-weighted thermometry with T1 thermometry using a 3D spiral ultra-short-echo time sequence and show that T1 thermometry is feasible, but requires further acceleration, whereas T1-weighted thermometry results are nonlinear and inconsistent.

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