Abstract #4151

Towards Quantitative Myocardial Perfusion: Catheter-Based Arterial Input Function Measurements with Flow-Normalization

Simon Stephan¹, Simon Reiss¹, Thomas Lottner¹, Ali Caglar Özen¹, and Michael Bock¹

¹Dept. of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Freiburg, Germany

For quantitative myocardial perfusion measurements with intra-arterial contrast agent (CA) injection precise knowledge of the arterial input function (AIF) is needed. Not necessarily absolute values of the AIF are needed if blood flow measurements are used to normalize the perfusion maps. In this work it is shown for a constant-flow phantom that this method works and probable issues for transferring the method to in-vivo measurements are discussed.

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