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Abstract #4151

Towards Quantitative Myocardial Perfusion: Catheter-Based Arterial Input Function Measurements with Flow-Normalization

Simon Stephan1, Simon Reiss1, Thomas Lottner1, Ali Caglar Özen1, and Michael Bock1
1Dept. of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Freiburg, Germany

For quantitative myocardial perfusion measurements with intra-arterial contrast agent (CA) injection precise knowledge of the arterial input function (AIF) is needed. Not necessarily absolute values of the AIF are needed if blood flow measurements are used to normalize the perfusion maps. In this work it is shown for a constant-flow phantom that this method works and probable issues for transferring the method to in-vivo measurements are discussed.

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