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Abstract #4152

Development of an optimal head localizer for stereotactic neurosurgery at 7.0T with minimal image geometric distortions

Aaron E Rusheen1,2, Elise M Berning1, Dane T Bothun1, Ben T Gifford1, Stephan J Goerss1, Kirk M Welker3, John Huston3, Kevin E Bennet1,4, Yoonbae Oh1,5, Charles D Blaha1, Kendall H Lee1,5, and Fagan J Andrew3
1Department of Neurosurgery, Mayo Clinic, Rochester, MN, United States, 2Medical Scientist Training Program, Mayo Clinic, Rochester, MN, United States, 3Department of Radiology, Mayo Clinic, Rochester, MN, United States, 4Department of Engineering, Mayo Clinic, Rochester, MN, United States, 5Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States

7.0T MRI provides precise visualization and targeting of brain structures for image-guided stereotactic neurosurgery. However, image localizers used by stereotactic systems do not exist for 7.0T scanners. Challenges in their development include: the small bore creates geometric constraints that disallow use of conventional localizers, and the increased B0 increases geometric distortion, affecting registration accuracy. Here, a skull-contoured localizer utilizing point fiducials was designed to attach to a novel stereotactic frame. Extracranial distortion was thoroughly mapped using several optimized imaging sequences. This data was used to optimally place fiducials on the localizer, improving registration accuracy.

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