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Abstract #4307

Practical considerations of DW-MRS with ultra-strong diffusion gradients

Christopher Jenkins1, Elena Kleban1, Lars Mueller1, John Evans1, Umesh Rudrapatna1, Derek Jones1, Francesca Branzoli2, Itamar Ronen3, and Chantal M.W Tax1
1CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom, 2Centre for NeuroImaging Research - CENIR, Brain and Spine Institute - ICM, Paris, France, 3Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

Diffusion-weighted magnetic resonance spectroscopy benefits from the use of ultra-strong gradients. Slow diffusing metabolites necessitate a large range of b-values to accurately model the diffusion properties. Ultra-strong gradients open the possibility of higher b-values and reduced diffusion times, alleviating some of these constraints. We present initial data acquired with DW-PRESS on a 300mT/m gradient Connectom scanner, and introduce the practical considerations associated with ultra-strong gradients.

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