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Abstract #4306

Improving X-PROP with a more stable echo train for diffusion weighted MRI

Zhiqiang Li1, Melvyn B Ooi1,2, and John P Karis1
1Neuroradiology, Barrow Neurological Institute, Phoenix, AZ, United States, 2Philips Healthcare, Gainesville, FL, United States

EPI-based DWI is widely used in the clinic but suffers from geometric distortions. DW-PROPELLER, based on FSE, is free from geometric distortions but has low scan efficiency. X-PROP was developed to improve FSE-based DW-PROPELLER scan efficiency by employing a GRASE readout. Although more efficient, XY2 phase modulation used in X-PROP is sensitive to the flip angles of the RF pulse train. This project improves X-PROP image quality by incorporating LRX phase modulation to increase SNR and signal stability. Image quality improvement was illustrated by comparing in vivo images produced with LRX phase modulation, XY2 phase modulation, and SPLICE PROPELLER imaging.

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