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Abstract #4363

Towards the clinical application of model‐based reconstruction framework for distortion correction in prostate diffusion weighted MRI.

Lebina Shrestha Kakkar1, Muhammad Usman1, Alex Kirkham2, Simon Arridge1, and David Atkinson1
1Centre for Medical Imaging, University College London, London, United Kingdom, 2Department of Radiology, University College Hospital, London, United Kingdom

Prostate diffusion-weighted (DW) MRI based on single-shot echo planar imaging (EPI) can suffer from geometric distortions caused by off-resonance magnetic field at the prostate-rectal air interface. Although techniques exist for effective distortion correction in brain imaging, such approaches may struggle with the severe distortions observed in prostate imaging. Here we focus on applying a recently developed model-based reconstruction technique to correct distortions in typical clinically used prostate DW-MRI. The distortion correction is feasible and may improve prostatic zonal anatomy in DW-MRI. Additionally, corrected averaged high b-value datasets show higher SNR than uncorrected dataset and may further help to identify tumours.

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