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Abstract #4448

Comprehensive analysis of full-spectrum diffusion weighted MR images with Multimodal Anomalous Diffusion Method (MAD)

Frederick C. Damen1, Mirko Vukelich1, Nitu Saran1, and Kejia Cai1
1Radiology, University of Illinois at Chicago, CHICAGO, IL, United States

In physiological and pathological conditions in which multiple underlying tissue properties are expected to vary the diffusion weighted signal, the diagnostic value of conventional apparent diffusion coefficient (ADC) notably decreases. By fully dissecting the whole spectrum of diffusion weighted imaging (DWI) data from low to high b‑values, we developed a method to extract the anomalous diffusion parameters for four water milieus: flow, and, unrestricted, restricted, and highly restricted diffusion, thus, expounding upon the diverse diffusivity within a voxel.

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