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Abstract #4452

Brodmann atlas based non-Gaussion water diffusion analysis of normal tension glaucoma: A diffusion kurtosis imaging study

Xiaoxia Qu1, Lizhi Xie2, Qian Wang1, Ting Li1, Jian Guo1, and JunFang Xian1
1Radiology Department, Beijing Tongren Hospital, Capital Medical University, Beijing, China, 2GE Healthcare, MR Research China, Beijing, Beijing, China

To access the non-Gaussion water diffusion characteristic of normal tension glaucoma (NTG), we analyzed the diffusion parameters generated from diffusion kurtosis imaging (DKI). The parameters derived from DKI within changed brain regions of NTG group were reduced and involved the occipital lobe. The visual cortex in NTG group had lower degree of diffusional heterogeneity and microstructural complexity compared to normal control (NC) group.

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