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Abstract #4526

Rich-Club Organizational Changes Over the Course of Motor Recovery after First-Time Acute Stroke

Lu Wang1, Hing-Chiu Chang1, Peng Cao1, and Edward.S Hui1
1Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China

In this study we acquired diffusion data and motor functions from stroke patients at within 1 week, 1, 3 and 6 months and found rich-club organization remerged one month after stroke and high order regions were found at 6 months when patients functionally recovered. Feeder connections showed middle cost and high capacity while rich-club connections showed high cost and middle capacity at 6 months after stroke. Together these results suggest that there could be a potential relation between reemergence of rich-club organization and brain motor recovery.

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