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Abstract #4545

Diffusion-weighted imaging at ultra-low field MR for acute stroke detection: what can we see?

Tiago Timoteo Fernandes1, Marc Golub1, Andreia Freitas1, Sairam Geethanath2,3, and Rita Gouveia Nunes1
1ISR, IST - University of Lisbon, Lisbon, Portugal, 2Medical Imaging Research Centre, Dayananda Sagar Institutions, Bangalore, India, 3Magnetic Resonance Research Center, Columbia University, NY, DC, United States

The primary goal of MR in acute stroke imaging is to determine the ischemic tissue at risk. Since a narrow time window is available for treatment, an accessible point-of-care system is desirable. Ultra-low field MR (ULF) shows promise but suffers from low signal-to-noise ratios (SNR). We performed a theoretical study of the SNR and contrast-to-noise (CNR) ratios for a range of B0 fields, with corresponding tissue relaxation times, considering different gradient performances. Illustrative simulated DWI brain images are provided. Results suggest that despite the challenges, ULF is promising for imaging acute stroke lesions.

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