Abstract #4569

Mono-exponential bi-exponential and stretched-exponential diffusion imaging in characterization of nonalcoholic fatty liver disease

Xianfu Luo¹, Jing Ye¹, Weiqiang Dou², Jun Sun¹, and Wei Xia¹

¹Radiology, Clinical Medical School of Yangzhou University, Northern Jiangsu People’s Hospital, Yangzhou, China, ²GE Healthcare，MR Research China, Beijing, China

We aimed to compare mono-exponential bi-exponential and stretched-exponential diffusion-weighted imaging(DWI) model in characterizing nonalcoholic liver disease (NAFLD) by providing multiple quantitative parameters. The diagnosis performance for early detection nonalcoholic steatohepatitis (NASH) was compared using characteristic operating curve analysis. Stretched-exponential DWI performed as well as bi-exponential DWI and better than mono-exponential DWI in the noninvasive characterization of NAFLD severity.

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