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Abstract #4606

Assessment of Right Ventricular Systolic Abnormalities in Pediatric Repaired TOF Patients with Preserved EF: CMR Feature Tracking Analysis  

Rongzhen Ouyang1, Shuang Leng2, Liwei Hu1, Aimin Sun1, Qian Wang1, Xiaofen Yao1, Xiaodan Zhao2, Ru-San Tan2, Yong Zhang3, Liang Zhong2,4, and Yumin Zhong1
1Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China, 2National Heart Centre Singapore, Singapore, Singapore, 3GE Healthcare, Shanghai, China, 4Duke-NUS Medical School, National University of Singapore, Singapore, Singapore

Right ventricular (RV) ejection fraction (EF) <45% is insensitive for detecting systolic dysfunction due to pulmonary regurgitation after Tetralogy of Fallot repair (rTOF). In pediatric rTOF patients with RVEF≥45% and healthy controls, CMR feature tracking was used to assess RV systolic strains and displacement as well as systolic and diastolic myocardial velocities. We observed abnormal RV global longitudinal strain and myocardial velocities in rTOF despite normal RVEF. 78% and 75% of rTOF patients had tricuspid annular displacement systolic excursion <10.9 mm and peak systolic myocardial velocity <6.3cm/s (lower normal limits among controls), respectively, indicating high prevalence of systolic functional impairment.

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