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Abstract #4633

Visual processing activation in the magnocellular pathway is associated with Developmental Dyslexia

Denis Peruzzo1, Sara Mascheretti2, Chiara Andreola2,3, Gabriele Amorosino1,4, Stefania Tirelli1, Daniela Redaelli1, and Filippo Arrigoni1
1Neuroimaging Unit, IRCCS Eugenio Medea, Bosisio Parini, Italy, 2Child Psychopathology Unit, IRCCS Eugenio Medea, Bosisio Parini, Italy, 3Laboratory for the Psychology of Child Development and Education (LaPsyDE), University Paris Descartes, Paris, France, 4NeuroInformatics Laboratory (NILab), Bruno Kessler Foundation, Trento, Italy

According to the magnocellular (M) deficit theory, deficits in the visual M functions predict reading skills and are associated with Developmental Dyslexia (DD). We acquired two well-established visual tasks (i.e. a sinusoidal grating and a coherent dots motion detection) in 22 Normal Readers (NR) and 22 children with DD. We applied a multi-variate pattern analysis approach to combine the two tasks. The combination of their activation patterns significantly discriminated between NR and children with DD, suggesting that differences in the M functions are present between the two populations and supporting the M deficit theory

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