Abstract #4633

Visual processing activation in the magnocellular pathway is associated with Developmental Dyslexia

Denis Peruzzo¹, Sara Mascheretti², Chiara Andreola^2,3, Gabriele Amorosino^1,4, Stefania Tirelli¹, Daniela Redaelli¹, and Filippo Arrigoni¹

¹Neuroimaging Unit, IRCCS Eugenio Medea, Bosisio Parini, Italy, ²Child Psychopathology Unit, IRCCS Eugenio Medea, Bosisio Parini, Italy, ³Laboratory for the Psychology of Child Development and Education (LaPsyDE), University Paris Descartes, Paris, France, ⁴NeuroInformatics Laboratory (NILab), Bruno Kessler Foundation, Trento, Italy

According to the magnocellular (M) deficit theory, deficits in the visual M functions predict reading skills and are associated with Developmental Dyslexia (DD). We acquired two well-established visual tasks (i.e. a sinusoidal grating and a coherent dots motion detection) in 22 Normal Readers (NR) and 22 children with DD. We applied a multi-variate pattern analysis approach to combine the two tasks. The combination of their activation patterns significantly discriminated between NR and children with DD, suggesting that differences in the M functions are present between the two populations and supporting the M deficit theory

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