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Abstract #4635

Functional Correlates to Achieving Early Motor and Language Milestones 

Muriel Marisa Katharina Bruchhage1,2, Giang-Chau Ngo1,2, Viren D'Sa1,2, and Sean C. L. Deoni1,2,3
1Warren Alpert Medical School, Brown University, Providence, RI, United States, 2Advanced Baby Imaging Lab, Hasbro Children's Hospital, Providence, RI, United States, 3Maternal, Newborn, and Child Health Discovery & Tools, Bill & Melinda Gates Foundation, Seattle, WA, United States

Developmental milestones are essential for a child’s development, with early milestones building a stepping-stone for more complex skills later. In this study, we investigate resting state functional connectivity (fc) before and after major developmental milestones (walking, pincer grasp, first words) were reached in a large cohort of typically developing children (3 to 30 months). Reaching a milestone showed a different fc pattern across all skill domains. Opposite to more complex skills where fc strengthened with skill advancement, walking recruited fewer fc networks when the milestone was reached, possibly underlining the importance of automaticity and complexity demand for the milestone achieved.

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