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Abstract #4637

The subregion scheme of the precuneus in children with autism spectrum disorder: a multimodal network analysis based on the Brainnetome Atlas

Xin Xu1,2 and Qiyong Gong1,2
1Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan Uinversity, Chengdu, China, 2Psychoradiology Research Unit of the Chinese Academy of Medical Sciences (2018RU011)), West China Hospital of Sichuan Uinversity, Chengdu, China

To explore the brain network characteristics in children with ASD, we calculated the whole-brain structural and functional connectivity and its network topological attributes between ASD children and typical development (TD) by using whole-brain multimodal connectivity network analysis based on the Brainnetome Atlas. This study found that the left dorsomedial parieto-occipital sulcus was the area of overlap within both structural and functional connectivity abnormalities in ASD children compared with TD, implicated that this subregion of the precuneus was a key node in ASD brain network during childhood.

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