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Abstract #4640

Structural and Functional changes in ventral and dorsal stream during phonological and haptic language in early and late blind

A Ankeeta1, s Senthil Kumaran1, and Rohit Saxena2
1NMR and MRI facility, All India Institute of Medical Sciences, New Delhi, India, 2RP centre, Opthalmology, All India Institute of Medical Sciences, New Delhi, India

Anatomical and functional MRI data for Braille and phonological noun pair assessment test was acquired in 40 early blind (EB), forty late blind (LB) subjects and thirty sighted controls (SC) in two age groups 6-12 years and 13-19 years (all right-handed). Visual impairment induces structural and functional modification in the visual cortex. Late blind subjects exhibited differences in the V1 13-19 years age range, but not in the 6-12 years age group. Duration of blindness and education influence the extent of plasticity of the V1 and language network.

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