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Abstract #4657

Infant Diets, Brain Cortical Development, and Executive Functions in Children

Ting Li1,2, Thomas M Badger3, Betty Jayne Bellando3, Seth Sorensen3, and Xiawei Ou1,3,4
1Arkansas Children's Research Institute, LITTLE ROCK, AR, United States, 2University of Arkansas at Little Rock, LITTLE ROCK, AR, United States, 3University of Arkansas for Medical Sciences, LITTLE ROCK, AR, United States, 4Arkansas Children's Nutrition Center, LITTLE ROCK, AR, United States

While it is known that breastfeeding promotes healthy brain development in children, the comparative effects of formulas feeding substantially differing in composition (i.e., milk-based vs. soy-based) on brain development are unclear. In this study, we recruited healthy 8-year-old children who were predominately breastfed, cow’s milk formula fed, or soy-based formula fed during infancy, and evaluated their brain cortical development using MRI. We also assessed their executive functions using parental-reported Behavior Rating Inventory of Executive Function (BRIEF) assessment. Differences in cortical thickness in multiple brain regions and differences in BRIEF scores were both observed for children in different infant diet groups.

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