Abstract #4658

The Morphological Development of Hand Knob Areas in Children Aged 6m to 10 years

Fan Wu¹, Xianjun Li¹, Yuli Zhang¹, Miaomiao Wang¹, Congcong Liu¹, Xiaoyu Wang¹, Chao Jin¹, Mengxuan Li¹, Cong Tian¹, Peiyao Chen¹, Xiaocheng Wei², and Jian Yang¹

¹Department of Diagnostic Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China, ²MR Research China, GE Healthcare, Xi'an, China

The cortical representation of hand motor function, hand knob region, is localized in the precentral gyrus. We found that the age-related rapid development of hand knob areas peaks at 4-5 years, and the left side increases faster than right. And the different increase rate between the left and right hand knob regions of normal children may be related to dominant hemisphere of handedness. This study will help to understand the process of hand function development in children and provide the research basis for the study of the upper limb pathway of the nerve center.

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