Abstract #4659

Tailored rehabilitation in developmental dyslexia based on neurobiological model

Sunita Gudwani^1,2, S.Senthil Kumaran³, Rajesh Sagar⁴, Madhuri Behari⁵, Manju Mehta⁶, Vaishna Narang⁷, SN Dwivedi⁸, and NR Jagannathan³

¹Department of ENT, Escorts Heart Institute and Research Center, New Delhi, India, ²Former Department of NMR and MRI Facility, Former ALL INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, India, ³Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, ⁴Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India, ⁵Department of Neurology, Fortis Hospital, New Delhi, India, ⁶Department of Psychiatry (Psychology Unit), All India Institute of Medical Sciences, New Delhi, India, ⁷Department of Linguistics, School of Language, Jawahar Lal Nehru University, New Delhi, India, ⁸Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India

Reading a cultural invention by human species is complex cognitive skill. The ventral regions contribute as integrating bottom-up (feed-forward) generic visual processing with top-down influences from phonological and semantic areas. Developmental dyslexia a neurodevelopmental disorder, despite its description since century ago is yet unclear. The heterogeneous deficits, persists and may have emotional-socio-economic consequences. The study shows that if domain specific remediation, tailored according to subject’s neurobiological positive and negative signs along with behavioral measures, it benefits the individuals. Post-training improvement in behavioral performance and reorganizations in neural processing towards normalization, rather than compensatory regions attributed to optimal outcome

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