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Abstract #4660

Hemispheric asymmetry of brain motor-related white matter:a diffusion kurtosis imaging study

Yuli Zhang1, Xianjun Li1, Mengxuan Li1, Chao Jin1, Miaomiao Wang1, Qinli Sun1, Fan Wu1, Congcong Liu1, Yannan Chen1, Xiaoyu Wang1, Huifang Zhao1, Cong Tian1, Peiyao Chen1, Xiaocheng Wei2, and Jian Yang1
1the First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China, 22. MR Research China, GE Healthcare, Xi'an, China, China

Motor function development is a necessary condition for later life. It is closely related to cognitive psychological development1. As an important white matter reflecting the motor function, clarify the asymmetry of corticospinal tract (CST) development, which is of great significance for revealing the developmental of behavior and exploring the mechanism of disease2. This study aims to use DKI parameters investigate the asymmetry of CST development. Our results suggest that from 0-13 years old, there is hemispheric asymmetry in the development of CST, and they show left-sided dominance ;the asymmetry of CST appears at 6 months.

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