Abstract #4749

Prebiopsy mpMRI to Increase the Detection Rate and Reduce the Overdiagnosis of Prostate Cancer

Sujeet Kumar Mewar¹, Sanjay Sharma², Sanjay Thulka³, Ekta Dhamijia³, Pradeep Kumar¹, Sridhar Panaiyadiyan⁴, Rama Jayasundar¹, S. Senthil Kumaran¹, S. Datta Gupta⁵, N.R. Jagannathan⁶, Rajeev Kumar⁴, and Virendra kumar¹

¹Department of NMR, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ²Department of Radio-diagnosis, RPC, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ³Department of Radio-diagnosis, IRCH, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ⁴Department of Urology, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ⁵Department of Pathology, All India Institute of Medical Sciences, New Delhi, India, Ansari nagar, India, ⁶Present address.Department of Radiology, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India

The results of the study showed that mpMRI guided in-bore biopsy has the potential to increase the detection rate of PCa. Prebiopsy mpMRI of prostate was used for identification of suspicious areas of malignancy which were targeted for PCa detection and reducing unnecessary biopsies. The detection rate was compared with TRUS guided 12 core biopsy. The data also indicated that using prebiopsy mpMRI may also help to reduce unnecessary biopsies. The PCa detection rate of in-bore mpMRI targeted biopsy was 53.84 % compared to 37.27% for TRUS guided biopsy.

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