The results of the study showed that mpMRI guided in-bore biopsy has the potential to increase the detection rate of PCa. Prebiopsy mpMRI of prostate was used for identification of suspicious areas of malignancy which were targeted for PCa detection and reducing unnecessary biopsies. The detection rate was compared with TRUS guided 12 core biopsy. The data also indicated that using prebiopsy mpMRI may also help to reduce unnecessary biopsies. The PCa detection rate of in-bore mpMRI targeted biopsy was 53.84 % compared to 37.27% for TRUS guided biopsy.