Abstract #4750

Improving tumor-tissue contrast by increasing spatial resolution

Jinghua Wang^1,2, Kim M Cecil¹, Mary Gaskill-shipley^1,2, Lili He^3,4, Bin Zhang⁵, Michael Lamba⁶, Lily Wang¹, and Achala Vagal¹

¹Radiology, University of Cincinnati, Cincinnati, OH, United States, ²Brain Tumor Center, University of Cincinnati, Cincinnati, OH, United States, ³Pediatrics, University of Cincinnati, Cincinnati, OH, United States, ⁴The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States, ⁵Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States, ⁶Radiation Oncology, University of Cincinnati, Cincinnati, OH, United States

There is broad agreement that increased tumor-tissue contrast significantly improves tumor visibility. It is not yet clear whether increasing spatial resolution will improve tumor-tissue contrast. In this study, we found that the increasing spatial resolution can significantly increase tumor-tissue contrast when tumor size is comparable to the spatial resolution, but provides an invariant contrast when tumor size is much larger than the spatial resolution.

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