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Abstract #4750

Improving tumor-tissue contrast by increasing spatial resolution

Jinghua Wang1,2, Kim M Cecil1, Mary Gaskill-shipley1,2, Lili He3,4, Bin Zhang5, Michael Lamba6, Lily Wang1, and Achala Vagal1
1Radiology, University of Cincinnati, Cincinnati, OH, United States, 2Brain Tumor Center, University of Cincinnati, Cincinnati, OH, United States, 3Pediatrics, University of Cincinnati, Cincinnati, OH, United States, 4The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States, 5Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States, 6Radiation Oncology, University of Cincinnati, Cincinnati, OH, United States

There is broad agreement that increased tumor-tissue contrast significantly improves tumor visibility. It is not yet clear whether increasing spatial resolution will improve tumor-tissue contrast. In this study, we found that the increasing spatial resolution can significantly increase tumor-tissue contrast when tumor size is comparable to the spatial resolution, but provides an invariant contrast when tumor size is much larger than the spatial resolution.

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