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Abstract #4766

Combine the different DWI biological inspirations including cellularity, vascularity and structural complexity to grade rectal cancer

Zhijun Geng1, Yunfei Zhang2, Shaohan Yin1, Shanshan Lian1, Haoqiang He1, Hui Li1, Chuanmiao Xie1, and Yongming Dai2
1Sun Yat-sen University Cancer Center, Guangzhou, China, 2United Imaging Healthcare, Shanghai, China

Biological inspirations such as cellularity, vascularity and micro-structural complexity of diffusion weighted imaging (DWI) are of great significance during clinical practice. However, scarcely has the systematic integration of these biological inspirations been applied for clinical application. This research aims to systematically integrate cellularity, vascularity and micro-structural complexity derived from diffusion kurtosis imaging (DKI) and Intravoxel Incoherent Motions (IVIM) Imaging, explore their correlations and evaluate their diagnostic performance for grading rectal cancer. Results suggested that the integration of different DWI biological inspirations provided a more comprehensive characterization of tumor, holding great potential during clinical practice.

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