Abstract #4777

Multi-site evaluation of MR breast phantom with internal MR-visible liquid crystal thermometer: initial temperature and DWI measurements

Lisa J Wilmes¹, David C Newitt¹, Wen Li¹, Evelyn Proctor¹, Natsuko Onishi¹, Teffany Joy Bareng¹, Tom L Chenevert ², Dariya I Malyarenko², Patrick J Bolan³, Todor Karaulanov⁴, Nola M Hylton¹, and Kathryn E Keenan⁵

¹University of California San Francisco, San Francisco, CA, United States, ²University of Michigan Medical School, Ann Arbor, MI, United States, ³University of Minnesota Medical School, Minneapolis, MN, United States, ⁴QalibreMD, Boulder, CO, United States, ⁵National Institute of Standards and Technology, Boulder, CO, United States

A multiparametric breast phantom with an integrated MRI-“visible” liquid crystal (LC) thermometer for real-time monitoring of phantom temperature was evaluated at three imaging sites, on MRI scanners from different vendors. Short-duration MRI acquisitions were optimized for visualization of LC elements and implemented at the sites for temperature measurements before and after DWI acquisitions. MRI-measured temperature differences between different imaging experiments were reflected in different water ADC values, calculated from DWI, that were consistent with the relationship between ADC and temperature described in the literature.

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