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Abstract #4803

Reproducibility of intravoxel incoherent motion MRI of pancreas tumor and healthy pancreas

TING YIN1, Chao Ma2, Shiyue Chen2, Rolf Gruetter1, and Jianping Lu2
1CIBM-AIT, École polytechnique fédérale de Lausanne, Lausanne, Switzerland, 2Department of Radiology, Changhai Hospital of Shanghai, Shanghai, China

Intravoxel Incoherent Motion (IVIM) model has shown the potential of contrast free perfusion estimation in pancreatic diseases study, while IVIM quantification is challenging for conventional free-breathing DWI data due to the presence of high level noise. In this study, we demonstrated that motion correction and denoising can improve the sampling accuracy which allows for pixel-wise parametric maps with acceptable reproducibility.

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