Abstract #4816

The correlation analysis of 3D APT with the parameters of 3D MR spectroscopy in glioma patients: an image-guided intraoperative pilot study

Xiaoluo Zhang¹, Dongxiao Zhuang¹, Jilei Zhang², Jianqing Sun², Weibo Chen², and Jinsong Wu¹

¹Glioma Surgery Division, Neurologic Surgery Department, Huashan Hospital, Fudan University, Shanghai, China, ²Clinical Science, Philips Healthcare, Shanghai, China

Our study is the first research to investigate the relationship between 3D APT and 3D MRS on individual level. The APTw values were correlated with the metabolite concentrations or ratios of MRS, especially Cho concentration. We proposed that 3D APT can be potentially used in intra-operation system to guide surgical biopsy and tumor resection.

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