To study the feasibility of intensity modulated radiotherapy (IMRT) plan which designed for nasopharyngeal carcinoma (NPC) based on MRI-only comparing the dosimetric difference of different CT value assignment methods on dose calculation. Pseudo CT were generated by different assignment methods based on simulation CT. The areas with a difference of more than 1% were mainly distributed in the air cavity, bone periphery and the skin. The assignment method of each tissue and organs were set to Populate CT value compared with other methods has the least influence on the dose calculation of NPC-IMRT plan, which could meet the clinical requirements.
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