Abstract #4837

The Investigation of Internal Target Volume（ITV）Definition For Radiation Therapy of Hepatocellular Carcinoma Guided Using 4D-MR-T2 Images

Yinxing Wang¹, Jianxin Ren¹, Guanzhong Gong¹, Weibo Chen², Marijn Kruiskamp³, and Yong Yin¹

¹Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China, ²Philips Healthcare, Shanghai, China, ³Philips Healthcare, BIU ADI MR Therapy Clinical Science, Amsterdam, Netherlands

In this study, we did the research of the feasibility and advantage in defining the ITV for RT of HCC guided by 4D-MR-T2 images compared to 4D-CT images. It had been found that gross tumor target volume and internal tumor target volume boundaries could be displayed clearly on 4D-MR-T2 images. The position and deformation status of liver and tumors could be monitored easily on 4D-MR-T2 images. 4D-MR-T2 Images should be the first choice for simulation of HCC to define the ITV, and establish adaptive RT approach for HCC.

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