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Abstract #4837

The Investigation of Internal Target Volume(ITV)Definition For Radiation Therapy of Hepatocellular Carcinoma Guided Using 4D-MR-T2 Images

Yinxing Wang1, Jianxin Ren1, Guanzhong Gong1, Weibo Chen2, Marijn Kruiskamp3, and Yong Yin1
1Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China, 2Philips Healthcare, Shanghai, China, 3Philips Healthcare, BIU ADI MR Therapy Clinical Science, Amsterdam, Netherlands

In this study, we did the research of the feasibility and advantage in defining the ITV for RT of HCC guided by 4D-MR-T2 images compared to 4D-CT images. It had been found that gross tumor target volume and internal tumor target volume boundaries could be displayed clearly on 4D-MR-T2 images. The position and deformation status of liver and tumors could be monitored easily on 4D-MR-T2 images. 4D-MR-T2 Images should be the first choice for simulation of HCC to define the ITV, and establish adaptive RT approach for HCC.

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