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Abstract #4858

Texture analyses based on multiple high b-value diffusion-weighted imaging (DWI) for evaluation of tumor heterogeneity in prostate cancer

Jingjun Wu1, Ailian Liu1, Jiazheng Wang2, Liangjie Lin2, Lihua Chen1, Qingwei Song1, Renwang Pu1, and Bingbing Gao1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China

In the current study, multiple high b-value DWI-based texture analysis was applied to evaluate tumor heterogeneity in prostate cancer patients. Parameters, including MinIntensity, MedianIntensity, MeanValue, and Skewnesswere were significantly different among DWI images with different b values. Therefore, texture analysis based on DWI maps with different b values may serve as a preoperative and non-invasive method for evaluating heterogeneity of prostate cancer.

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