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Abstract #4859

Diffusion Kurtosis Imaging and Intravoxel Incoherent Motion MR Imaging in the Differentiation of  Sinonasal Malignant Tumors

Zuohua Tang1, Zebin Xiao1, Peng Wang1, and Zhongshuai Zhang2
1Radiology, Fudan University Eye & ENT Hospital, Shanghai, China, 2MR Scientific Marketing, Siemens Healthcare, Shanghai, China

A reliable differentiation of different histological types of sinonasal malignancies is usually difficult by using conventional CT and MR imaging but plays an important role in determining the treatment strategies for the patients. This is the first study which combined DKI and IVIM to distinguish among four histological types of sinonasal malignant tumors, including squamous cell carcinomas (SCCs), olfactory neuroblastomas (ONBs), malignant melanomas (MMs), and lymphomas. Our study showed that these sinonasal malignant tumors had distinct profiles in DKI and IVIM parameters, determined by different proportions of tissue complexity, capillary perfusion, or water diffusion components within tumor.

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