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Abstract #4870

IVIM & Diffusion Kurtosis MR Imaging on Interim Response Assessment of Hodgkin Lymphoma

Archana Vadiraj Malagi1, Devasenathipathy Kandasamy2, Kedar Khare3, Deepam Pushpam4, Rakesh Kumar5, Sameer Bakhshi4, and Amit Mehndiratta1,6
1Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, India, 2Department of Radiodiagnosis, All India Institute of Medical Sciences Delhi, New Delhi, India, 3Indian Institute of Technology Delhi, New Delhi, India, 4Department of Medical Oncology, Dr. B.R. Ambedkar Institute-Rotary Cancer Hospital (IRCH), All India Institute of Medical Sciences Delhi, New Delhi, India, 5Department of Nuclear Medicine, All India Institute of Medical Sciences Delhi, New Delhi, India, 6Department of Biomedical Engineering, All India Institute of Medical Sciences Delhi, New Delhi, India

PET/CT plays an important role in assessment of treatment response in Hodgkin lymphoma (HL). This study goal was to evaluate the role of IVIM and DKI parameters role in interim assessment of HL. ADC, D(BE+TV), Dk and f showed reduction in interim which was in accordance with changes of SUVmax and SUVmean whereas D* and k showed increase against treatment response. In future, IVIM and DKI can have the potential in accurate assessment of interim monitoring in HL.

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