Abstract #4870

IVIM & Diffusion Kurtosis MR Imaging on Interim Response Assessment of Hodgkin Lymphoma

Archana Vadiraj Malagi¹, Devasenathipathy Kandasamy², Kedar Khare³, Deepam Pushpam⁴, Rakesh Kumar⁵, Sameer Bakhshi⁴, and Amit Mehndiratta^1,6

¹Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, India, ²Department of Radiodiagnosis, All India Institute of Medical Sciences Delhi, New Delhi, India, ³Indian Institute of Technology Delhi, New Delhi, India, ⁴Department of Medical Oncology, Dr. B.R. Ambedkar Institute-Rotary Cancer Hospital (IRCH), All India Institute of Medical Sciences Delhi, New Delhi, India, ⁵Department of Nuclear Medicine, All India Institute of Medical Sciences Delhi, New Delhi, India, ⁶Department of Biomedical Engineering, All India Institute of Medical Sciences Delhi, New Delhi, India

PET/CT plays an important role in assessment of treatment response in Hodgkin lymphoma (HL). This study goal was to evaluate the role of IVIM and DKI parameters role in interim assessment of HL. ADC, D(BE+TV), Dk and f showed reduction in interim which was in accordance with changes of SUVmax and SUVmean whereas D* and k showed increase against treatment response. In future, IVIM and DKI can have the potential in accurate assessment of interim monitoring in HL.

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