Diffusion tensor distribution (DTD) imaging was applied in a pilot study to investigate the potential for breast tumor grading in a clinical setting. The method relies on advanced gradient waveforms to encode the signal with information about cell densities, shapes, and orientations, and quantify tissue composition as a probability distribution in a space with dimensions analogous to the cellular ones. Five patients with ductal carcinoma underwent a <4 min DTD protocol giving voxel-resolved distributions and parameter maps with microstructural information not accessible with conventional methods, thereby encouraging future studies with larger patient groups and comparison with current gold standards.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords