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Abstract #0007

Fast 2D J-resolved MRSI combining echo planar imaging acquisition and turbo spin echo train evolution

Ke Dai1, Qingjia Bao2,3, Hao Chen1, Yiling Liu1, and Zhiyong Zhang1
1School of Biomedical Engineering, Shanghai, China, 2Wuhan United Imaging Life Science Instruments Co., Ltd, Wuhan, China, Wuhan, China, 3Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, Israel

J-resolved MRSI is a powerful tool for separating overlapping resonances and detecting coupled species such as GABA and glutamate, which are of great interest to brain studies. However, a major practical limitation of J-resolved MRSI lies in its long data acquisition time. In this work, we present a novel fast fully sampled 2D J-resolved MRSI, termed as J-resolved xSPEN spectroscopy, combining echo planar imaging acquisition and turbo spin echo train evolution. Our preliminary phantom results demonstrate the proposed method can achieve highly efficient fully sampled 2D J-resolved MRSI with increasing chemical shift separation and detection of coupled species.

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