Conventional clinical cardiac MRI protocols use a large number (>20) of breath-holds for capturing cinemagraphic (CINE) scans of the heart in various views. We hypothesize simultaneous multi-slice (SMS) CINE can be further accelerated using a reduced FOV and a novel approach based on Region-Optimized Virtual (ROVir) coils, which can potentially achieve single breath-hold whole heart CINE. We demonstrated the feasibility of combining SMS and ROVir for highly accelerated CINE imaging (8-fold reduced scan time), enabling single breath-hold whole ventricular acquisition. Single breath-hold SMS+ROVir whole-heart CINE yielded cardiac function parameters with no significant bias when compared to SMS CINE.
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