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Abstract #0096

In vivo human T2* imaging at 0.35 mm reveals up to 15 ms of local variations within gray matter across depths at 7T

Omer Faruk Gulban1,2, Saskia Bollman3, Renzo Huber1, Kendrick Kay4, Benedikt Poser1, Federico De Martino1, and Dimo Ivanov1
1Department of Cognitive Neuroscience , Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 2Brain Innovation, Maastricht, Netherlands, 3Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, 4Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

We measured in vivo human brain T2* values using 7T MRI at 0.35 × 0.35 × 0.35 mm3. We simultaneously targeted calcarine sulcus and Heschl’s gyrus. Our results show that gray matter T2* varies up to 15 ms (global range being mostly in between 25-45 ms) from deep to superficial layers. The stria of Gennari shows up as a major reduction of T2* within calcarine sulcus. However, a similar layering is not visible within Heschl’s gyrus. B0 alignment effects seem to be not as strong as the biological tissue composition effects that are observed across the visual and auditory regions.

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