Intra-hippocampal perfusion patterns have remained unexplored so far but might carry important information to study disease pathogenesis. In this study we used arterial spin labeling (ASL) combined with time-of-flight angiography acquired at 7T to delineate perfusion and the effects of vascularisation patterns across the hippocampal subfields. We found that (i) imaging hippocampal perfusion in vivo is feasible using ASL at 7T, (ii) perfusion could serve as biomarker to differentiate hippocampal subfields, but that (iii) the impact of the dense macrovascular network varies based on characteristics such as distance and diameter.
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