Diffusion-relaxation correlation NMR methods have recently received attention from the medical MRI community for their ability to characterize microstructure and local chemical composition in complex tissues containing multiple subvoxel pools of water. We here implement 6D $$$\bf{D}$$$-$$$R_1$$$-$$$R_2$$$ distribution imaging of the human brain using a 20-min acquisition protocol combining EPI signal read-out and tensor-valued diffusion encoding with varying repetition- and echo times. Monte Carlo data inversion yields nonparametric distributions, statistical descriptors, and orientation-resolved diffusion and relaxation properties of white matter fiber bundles that are in good agreement with previous results from less exhaustive 4D and 5D protocols.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords