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Abstract #0110

SNR efficiency and effectiveness of 7T high-b diffusion imaging with MESMERISED and PGSE

Alard Roebroeck1, Benedikt A Poser1, and Francisco J Fritz2
1Department of Cognitive Neuroscience, Faculty of Psychology & Neuroscience, Maastricht University, Maastricht, Netherlands, 2Department of Systems Neurosciences, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Hamburg, Germany

We compare MESMERISED and standard PGSE for their signal-to-noise efficiency in b-value = 7000 s/mm2 (b7k) dMRI at 7T and their effectiveness in supporting microstructure modeling. At current state-of-the-art gradient performance, MESMERISED’s SAR and gradient duty cycle efficiency allows it to outperform PGSE for 7T high-b dMRI and provide highly efficient and effective microstructure modeling. Its added capacity to explore diffusion times, super-accelerate quantitative T1 mapping, and also perform qT2 and B1+ mapping, makes it highly useful for quantitative multi-contrast and diffusion MRI.

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