We compare MESMERISED and standard PGSE for their signal-to-noise efficiency in b-value = 7000 s/mm2 (b7k) dMRI at 7T and their effectiveness in supporting microstructure modeling. At current state-of-the-art gradient performance, MESMERISED’s SAR and gradient duty cycle efficiency allows it to outperform PGSE for 7T high-b dMRI and provide highly efficient and effective microstructure modeling. Its added capacity to explore diffusion times, super-accelerate quantitative T1 mapping, and also perform qT2 and B1+ mapping, makes it highly useful for quantitative multi-contrast and diffusion MRI.
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