This study presents a DL based framework for correcting B0 inhomogeneity for GluCEST imaging using fewer acquisitions. Based on 3 or 5 positive offset CEST images, the proposed method can save >80% of CEST imaging acquisition time as compared to current 26 pairs of double site z-spectrum irradiations based protocol. This approach can be applied to other CEST imaging as well.
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