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Abstract #0147

Diffusion-weighted Chemical Exchange Saturation Transfer Imaging at 7T Human MRI

Yujin Jung1, Jaeseok Park2, Seong-Gi Kim2, and Sung-Hong Park1
1Department of Bio and Brain engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of, 2Department of Global Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of

CEST is a useful method to diagnose tumor or stroke, but lacks physical information such as compartments with different diffusivities. In this study, we developed a new diffusion-weighted steady-state CEST sequence using 3D EPI at 7T. The technique was tested in phantom and human brain, and the preliminary CEST-weighted apparent diffusion coefficient maps provided both CEST and diffusion information. Further study is required to clearly understand the signal source and the potential as a new biomarker.

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