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Abstract #0154

Utility of Adiabatic T1Ρ and T2Ρ Mapping to Detect Ischemic Injury to the Femoral Head: An In Vivo Piglet Model Study at 3T MRI

Casey P. Johnson1,2, Sampada Bhave1, Alexandra R. Armstrong1, and Ferenc Toth1
1Department of Veterinary Clinical Sciences, University of Minnesota, Saint Paul, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

Adiabatic T1ρ and T2ρ are potentially advantageous relaxation time mapping techniques for in vivo imaging of the musculoskeletal system. In this work, we compared adiabatic T1ρ and T2ρ mapping to T2 and continuous-wave T1ρ mapping in a piglet model of osteonecrosis of the femoral head. We found that adiabatic T2ρ had a robust increase in response to ischemic injury to the bone marrow, bone, and epiphyseal cartilage of the ischemic femoral head compared to the contralateral healthy femoral head. Adiabatic T2ρ may be a useful technique to detect early-stage injury in ischemic bone and joint disorders.

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