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Abstract #0153

Formalism of the T1Ρ* relaxation pathway: Correction of quantification errors for rapid myocardial T1Ρ mapping in mice

Maximilian Gram1,2, Daniel Gensler1,3, Patrick Winter1,2, Fabian Gutjahr2,3, Michael Seethaler2,3, Peter Michael Jakob2, and Peter Nordbeck1,3
1Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, 2Experimental Physics 5, University of Würzburg, Würzburg, Germany, 3Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany

The rapid quantification of T using fast gradient echo sequences for data acquisition leads to a contamination of the T relaxation pathway. Analogous to the T1* relaxation occurring in snapshot flash sequences, a relaxation pathway T* is effectively observed. As a consequence, quantification errors can arise depending on T1 and the sequence parameters used for imaging. In this work we introduce a formalism for the description of T* and present a method that can be applied for the subsequent correction of study results in the field of cardiac MRI.

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