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Abstract #0289

A method for high quality magnetic resonance spectroscopy of discs during normal breathing

Frida Johansson1,2, Helena Brisby2,3, Hanna Hebelka2,4, Maria Ljungberg1,2, and Kerstin Lagerstrand1,2
1Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, 2Institute of Clinical Sciences, Gothenburg University, Gothenburg, Sweden, 3Department of Orthopaedics, Sahlgrenska University Hospital, Gothenburg, Sweden, 4Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden

This study aimed to evaluate the effect of respiratory motion on disc MRS and propose an MRS-method that improves the signal-to-noise-ratio. Findings showed that the phase signal of the disc changes substantially between expiration and inspiration. With the proposed postprocessing method, all spectra gave a higher signal-to-noise-ratio (largest gain=30%). Present study shows that respiratory motion affects the disc phase signal and should be taken into consideration when evaluating the disc using MRS. The proposed method improved the quality of the MRS-spectrum and, thus, showed feasibility in measuring the molecular disc content non-invasively during normal breathing.

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